Metabolic health · Blood sugar · Gut health

Berberine

Berberine HCl 97%·See why we use it →

★★★★★ 4.6 (2,100 reviews) Third-party tested 50+ clinical trials independent

The Berberine bottle held in a real hand against a soft limestone background, cap just opened. Warm side light, shallow focus, adult and unhurried.

One Berberine HCl 97% dose and a glass of water on a stone bathroom counter, morning light. The product in its daily moment — calm, clean, no clutter.

Amber Berberine HCl 97% softgels poured from the bottle into an open palm in warm morning light — the daily dose, in real hands.

Dose VerifiedStudy VerifiedLot Verified

Third-party tested →

Non-GMO · Gluten-free · Made in USA

SourcedUttarakhand, India

MadeLindon, Utah

TestedBellingham, WA

1,000 mgthe exact dose the studies used

50+ clinical trialsindependent, peer-reviewed

3×tested before any lot ships

60-daymoney-back guarantee

The difference

What makes it different

97% berberine HCl

Standardized purity, not a vague 'complex.'

Two smaller capsules

The full 1,000 mg without the horse-pill.

Heavy-metal screened

It's a root. We test what the soil leaves behind.

Tested 3×

Supplier, our lab, then a third party.

Field note

Berberine has a reputation: a giant horse-pill that can wreck your stomach. We split it into two smaller capsules you take with food. Same full dose, far easier on your gut.

What it's good for

What it supports

Because we use Berberine HCl 97% — the exact ingredient and the exact dose the studies used, not a cheaper generic — we can stand behind what that research shows it supports:

✓

Healthy blood sugar

Supports glucose already in the normal range.

✓

Metabolic & AMPK support

Activates the same cellular energy sensor exercise does.

✓

Lipid balance

Studied for supporting healthy cholesterol and triglycerides.

✓

Gut & GLP-1

Works at the gut level, where metabolism quietly begins.

These are structure/function statements based on published studies of the ingredient, not on this finished product. They have not been evaluated by the Food & Drug Administration, and this product is not intended to diagnose, treat, cure, or prevent any disease.†

What's in it1,000 mg active The full supplement facts: 1,000 mg of Berberine HCl 97%, what carries it, and nothing else. No proprietary blends, no fillers.

What's inside

Serving SizeSee directions

Amount Per Serving

Berberine HCl (97%, from Berberis aristata)1,000 mg

Other ingredients: vegetable cellulose capsule. No proprietary blends, no fillers we can't justify. Free of gluten, dairy, soy, and GMOs. † Daily Value not established for some ingredients.

Directions

One capsule twice daily, with meals.

Berberine is only as good as its purity and dose, and most bottles cut both. Ours is 97% berberine HCl at the full 1,000 mg used in studies, split into two smaller capsules so it's not a horse-pill. Every batch is tested for heavy metals, since it's a root.

1,000 mgBerberine HCl (97%, from Berberis aristata)

0Proprietary blends or fillers we can't justify.

The research50+ clinical trials 50+ clinical trials on Berberine HCl 97%: what they found, with every citation linked so you can read it yourself.

We don't make the claims. The studies do. 50+ clinical trials on Berberine HCl 97% — read every one yourself.

The studies behind it

[01] Healthy blood glucose Yin et al., 2008 — Metabolism Read the study → [02] Cholesterol & lipid balance Kong et al., 2004 — Nature Medicine Read the study → [03] Pooled metabolic effects Lan et al., 2015 — J. Ethnopharmacology (meta-analysis) Read the study → [04] Type-2 diabetes (meta-analysis) Dong et al., 2012 — Evidence-Based Complementary Medicine Read the study → [05] Lipid-lowering (meta-analysis) Dong et al., 2013 — Planta Medica Read the study → [06] Insulin resistance & PCOS Wei et al., 2012 — European J. Endocrinology Read the study → [07] Gut microbiome modulation Zhang et al., 2015 — Scientific Reports Read the study →

Citations refer to published, peer-reviewed research on the ingredient — not on this finished product. Structure/function statements only, not evaluated by the FDA.† See all studies for Berberine →

Where it comes fromSourced → made → tested From Uttarakhand, India to your bottle. Every stage named, made in the USA, third-party tested before it ships.

01Sourced

Uttarakhand, India

Berberis aristata root from a traceable, audited Himalayan supplier.

→

02Standardized

Vetted GMP partner

Concentrated to 97% berberine HCl and identity-confirmed.

→

03Made

Lindon, Utah, USA

Encapsulated and bottled in an NSF-registered, cGMP facility.

→

04Verified

Third-party lab

Every lot assayed for potency and screened for heavy metals and pesticides.

Tested by the supplier → then in-house → then a third party

How we test every lot →

Order specification

$25.50 $30 Save 15%

★★★★★4.6 · 2,100 reviews

What people say about Berberine.

4.6

★★★★★

Based on 2,100 verified reviews

5★78%

4★16%

3★4%

2★1%

1★1%

Dana R. ✓ Verified

★★★★★ · 2 months ago

The only brand whose label I don't have to fact-check. I emailed for the COA on my lot and they sent it the same day.

Transparency

Paul M. ✓ Verified

★★★★★ · 3 weeks ago

Switched from Thorne. Same rigor, the dose is actually printed on the front, and it's a better price.

Switched brands

Marian K. ✓ Verified

★★★★★ · 5 days ago

I'm 67 and tired of guessing what's in my supplements. This one prints everything. My pharmacist looked at the label and approved.

Trust

Priya S. ✓ Verified

★★★★☆ · 1 month ago

Took about six weeks, but I notice the difference now. I appreciate that they tell you to give it time instead of overpromising.

Patience

Greg T. ✓ Verified

★★★★★ · 2 weeks ago

No gut issues, no aftertaste. Finally a brand that doesn't cut corners to save a few cents.

Easy on the stomach

Tom B. ✓ Verified

★★★★★ · 2 months ago

Was skeptical about the price until I actually read the third-party test report. You get what you pay for.

Skeptic

Sofia A. ✓ Verified

★★★★★ · 3 months ago

Bought it for my dad. He reads labels obsessively, and this is the only one he trusts now.

Gifting

Devon L. ✓ Verified

★★★★☆ · 6 weeks ago

Two capsules a day, easy to take. Wish the bottle were a touch bigger, but the quality is clearly there.

Daily use

Renee W. ✓ Verified

★★★★★ · 1 month ago

Clean, no fillers, and they answer emails like actual humans. Already re-ordered.

Service

Hassan M. ✓ Verified

★★★★★ · 3 weeks ago

The dose matches the studies they cite. That's the whole reason I bought it, and it delivered.

Studied dose

Sample reviews shown for design purposes.

FAQ

Does any of this actually work, or is it expensive pee?

Fair question. We only sell ingredients with human studies behind them, and we link every one. If your body doesn't need a nutrient, you'll pass it — so we tell you who each product is actually for.

How do I know it isn't underdosed?

We make one ingredient per product, at the amount the studies used, printed right on the front. There's no blend to hide a pinch behind.

What does “tested three times” mean?

The supplier tests it, our own lab tests it again, then an independent lab tests the finished batch — for potency, heavy metals, and microbes. Email us your lot number and we'll send the report.

If it's sourced abroad, how is it Made in the USA?

We buy each ingredient from wherever it's made best — Italian olive oil, Spanish saffron, Japanese fermentation. Every product is then made and bottled in Lindon, Utah.

I've tried things like this before and felt nothing.

Most of these studies run 8 to 12 weeks, so give it that long. If you still feel nothing, send it back within 60 days, opened or not, and we'll refund you.